Refractory malignant ascites
WebThe aim of this study was to investigate the efficacy and safety of intraperitoneal catumaxomab in heavily pretreated patients with chemotherapy-refractory ovarian cancer and recurrent symptomatic malignant ascites. Methods: Patients received 4 three-hour intraperitoneal catumaxomab infusions (10, 20, 50, and 150 μg within 10 days). WebFeb 27, 2024 · Malignant ascites from cancers of stomach, pancreas and biliary tract are more refractory to intravenous chemotherapy or intraperitoneal chemotherapy than ascites from ovarian or chemo-naïve colorectal cancers because of the inherent nature of chemoresistance.
Refractory malignant ascites
Did you know?
WebFeb 28, 2024 · Malignant ascites often causes discomfort in advanced cancer patients. Paracentesis is the most common treatment modality, but it requires frequently repeated … WebAscites is a frequent complication of cirrhosis and portal hypertension, because of the increase of the sinusoidal hydrostatic pressure. Cirrhosis accounts for over 75% of …
WebDisclosed is the use of a docetaxel polymer micelle in the preparation of a drug for preventing or treating malignant hydrothorax and ascites. The docetaxel polymer micelle is used for treating malignant hydrothorax and ascites, which can significantly prolong survival, improve the treatment effect of hydrothorax and ascites, increase the plasma exposure … WebSep 6, 2024 · Patients with diuretic-resistant ascites have pre-hepatorenal syndrome and a poor prognosis [ 2 ]. The two-year survival rate of all patients with cirrhosis after the development of ascites is approximately 50 percent [ 3,4 ]. By comparison, survival in patients with diuretic-resistant ascites is 50 percent at six months and 25 percent at one ...
WebFeb 8, 2024 · Ascites is the accumulation of fluid in the abdomen. The most common cause is liver damage or cirrhosis, but it can also be caused by heart failure, pancreatitis, infection, cancer, and more. Symptoms include nausea, vomiting, feeling full when eating, loss of appetite, and shortness of breath. WebJun 5, 2024 · In refractory-type ascites patients, there are a few situations. The medical treatment doesn’t fix the fluid buildup problem or it returns after the treatment ends. This …
WebObjective: This prospective, dose-escalation phase I study evaluated the safety and efficacy of intraperitoneal bevacizumab in managing refractory malignant ascites and explored the recommended dose of bevacizumab for further study. Methods: Patients with refractory malignant ascites were enrolled. Bevacizumab was intraperitoneal administered weekly at …
WebFeb 25, 2024 · Malignant peritoneal ascites confirmed by cytologic examination. Failures from chemotherapy or other anti-cancer therapy or standard chemotherapy was no longer … nausicaa valley of the wind lengthWebAscites remains the most common cirrhosis complication resulting in hospitalisation. Many patients with refractory ascites are not candidates for liver transplantation or transjugular … nausicaa valley of the wind manga pdfWebNational Center for Biotechnology Information markblossom4 twitterWebMar 24, 2024 · Conclusions PVS significantly improves the symptom of pain due to refractory ascites compared to other treatments. Although not as effective as improving the comprehensive QOL evaluated with... mark bloom networth realtyWebMar 31, 2024 · This study is to evaluate the safety, effectiveness of local immune activation, and efficiency in patients with refractory malignant ascites after Intraperitoneal injection of oncolytic Viruses H101 and Tislelizumab. Study Design Go to Arms and Interventions Go to Outcome Measures Go to Primary Outcome Measures : mark bloodgood home inspectorWebDec 29, 2024 · Therapeutic paracentesis may be performed in patients who require rapid symptomatic relief for refractory or tense ascites. When small volumes of ascitic fluid are … mark blot crossword clueWebTumor obstruction of the subdiaphragmatic lymphatics is one pathogenetic mechanism. 73 Malignant ascites can also result from nonobstructive factors including immunomodulators such as interleukin-2, tumor … nausicaa valley of the wind meaning