Irf1 molecular weight

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August undefined, 2024

WebJan 15, 2024 · Molecular and functional characterization of interferon regulatory factor 1 (IRF1) ... 10 μg/g body weight] for 3 h, whose spleen and kidney were used for the extraction of total RNA by using Trizol Reagent (Invitrogen). The first-strand cDNA was synthesized from above total RNA and served as template to amplify ORF sequence of Xt-IRF1 by PCR ... WebIRF1 as a transcriptional regulator which displays a remarkable functional diversity in the regulation of cellular responses. The calculated molecular weight of IRF1 is 37 kDa, but …

IRF1 antibody (11335-1-AP) Proteintech - ptglab

WebWe first generated Irf1 knockout (Irf1 KO) mice and observed exacerbated DSS-induced colitis phenotypes compared to their WT littermates (Irf1 WT) (Supplementary information, Fig. S8c–g ... WebMar 29, 2024 · IRF1 and IRF2 also appear to be important in regulating DC subset development— Irf −/− mice show a loss of splenic and epidermal DCs (due to augmented type I IFN signaling) ( 109, 110) whereas Irf1−/− exhibit an increase in pDCs and a decrease in CD8 + DCs in mice, along with an increase of IL-10 and TGF-β ( 111 ). bissendorf tiernothilfe

Molecular and functional characterization of interferon

WebApr 4, 2024 · IRF1 is involved in TLR- and cytokine-mediated signaling in human myometrium. 5AZ had a protective effect after MI by potentiation of IRF1 sumoylation and … WebApr 16, 2002 · Molecular Function: RNA polymerase II transcription regulatory region sequence-specific DNA binding Source:ARUK-UCL. 1 publication. ... Note: MYD88-associated IRF1 migrates into the nucleus more efficiently than non-MYD88-associated IRF1. By similarity Keywords. Cellular component. #Cytoplasm; #Nucleus ... WebPredicted molecular weight. 32.27 kDa . Stability and Storage. Use a manual defrost freezer and avoid repeated freeze thaw cycles.Store at 2 to 8 °C for one week .Store at -20 to -80 °C for twelve months from the date of receipt. ... IRF1. Species. Human . Shipping. In general, proteins are provided as lyophilized powder/frozen liquid. They ... bis service

IRF1 - phosphosite.org

WebIRF1 Antibodies. Antibodies that detect IRF1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry and Flow Cytometry. These antibodies target IRF1 in Human, Mouse and Rat samples. Our IRF1 polyclonal, recombinant monoclonal and monoclonal antibodies are developed ... WebDec 16, 2024 · Background Interferon regulatory factor 1 (IRF1) is an important transcription factor that activates the type I interferon (IFN-I) response and plays a vital role in the antiviral immune response. Although IRF1 has been identified in several mammals, little information related to its function in canines has been described. Results In this study, canine IRF1 … bisset and rossWebReference #: P10914 (UniProtKB) Alt. Names/Synonyms: Interferon regulatory factor 1; IRF-1; IRF1; MAR Gene Symbols: IRF1 Molecular weight: 36,502 Da Basal Isoelectric point: … bisseron plombier chamonix

"WebDec 1, 2024 · The predicted molecular weight of the Cf IRF1 protein was approximately 40 kDa. Using the SMART program and NCBI conserved domain search program, the N-terminus of the Cf IRF1 protein was predicted to encode an IRF1 domain, similar to IRF1 family proteins of other species ( Fig. 2 A ). Download : Download high-res image (2MB) " - Irf1 molecular weight

Irf1 molecular weight

Mouse Interferon Regulatory Factor 1 protein(ABIN3010103)

WebNov 26, 2024 · As expected, extracellular high molecular weight poly(I:C) did not induce Mda5 expression ... Twenty-four hours after transfection, the cells were stimulated for 3 h with IFN-α or LPS and Irf1 expression was determined by qPCR (n = 4) ... WebMar 21, 2024 · IRF1 (Interferon Regulatory Factor 1) is a Protein Coding gene. Diseases associated with IRF1 include Lung Cancer and Gastric Cancer. Among its related pathways are Bacterial infections in CF airways and Overview of interferons-mediated signaling … HBB (Hemoglobin Subunit Beta) is a Protein Coding gene. Diseases associated with … Gene Ontology (GO) - Molecular Function for MET Gene. GO ID Qualified GO term … VCAM1 (Vascular Cell Adhesion Molecule 1) is a Protein Coding gene. Diseases … Complete information for IWS1 gene (Protein Coding), Interacts With SUPT6H, … PHGDH (Phosphoglycerate Dehydrogenase) is a Protein Coding gene. Diseases … CCL2 (C-C Motif Chemokine Ligand 2) is a Protein Coding gene. Diseases … IFITM1 (Interferon Induced Transmembrane Protein 1) is a Protein Coding gene. … CCL19 (C-C Motif Chemokine Ligand 19) is a Protein Coding gene. Diseases … IGFBP7 (Insulin Like Growth Factor Binding Protein 7) is a Protein Coding gene. … CDKN1B (Cyclin Dependent Kinase Inhibitor 1B) is a Protein Coding gene. Diseases …

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WebJul 8, 2024 · IRF1 expression is associated with the expression of IFNβ, which leads to the activation of the JAK-STAT pathway. ... Consistently, molecular function enrichment … WebKO Validated STAR208P) and visualized on the ChemiDoc MP with 10 second exposure. Arrow points to IRF1 (molecular weight 47 kDa) Western blot analysis of IRF1 knockout HeLa and wild type HeLa (WT) whole cell lysates probed with (A) Rabbit anti IRF1 antibody (VPA00801STAR208P) and (B) hFAB rhodamine anti-tubulin primary antibody and …

WebJun 19, 2024 · This observation was further corroborated by molecular studies showing increased percentages of IL-17A/IFN-γ-producing CD4 + T cells in the central nervous … WebDescription Product name Recombinant Human IRF1 protein (His tag) Purity > 90 % SDS-PAGE. NULL Endotoxin level < 1.000 Eu/µg Expression system Escherichia coli Accession …

WebMay 5, 2014 · Cellular & Molecular Immunology - K63-linked polyubiquitination of IRF1: an essential step in the IL-1 signaling cascade ... Adding weight to this was the observation that SKI-1, ... WebDec 27, 2024 · Results: IRF1 was identified as a novel TF that suppresses KPNA2 gene expression. We observed that IRF1 expression was lower in cancerous tissues than in normal lung tissues and that its low expression was correlated with poor prognosis in …

• Harada H, Taniguchi T, Tanaka N (1999). "The role of interferon regulatory factors in the interferon system and cell growth control". Biochimie. 80 (8–9): 641–50. doi:10.1016/S0300-9084(99)80017-0. PMID 9865486. • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth". Biochimie. 80 (8–9): 651–8. doi:10.1016/S030… • Harada H, Taniguchi T, Tanaka N (1999). "The role of interferon regulatory factors in the interferon system and cell growth control". Biochimie. 80 (8–9): 641–50. doi:10.1016/S0300-9084(99)80017-0. PMID 9865486. • Pitha PM, Au WC, Lowther W, Juang YT, Schafer SL, Burysek L, Hiscott J, Moore PA (1999). "Role of the interferon regulatory factors (IRFs) in virus-mediated signaling and regulation of cell growth". Biochimie. 80 (8–9): 651–8. doi:10.1016/S0300-9084(99…

WebWhen using primary antibodies produced in mouse to detect proteins with a molecular weight in the range of 50 kDa, we recommend using Rabbit Anti-Mouse IgG (Light Chain … darth maul shadow collective saberWebObjectives: Although it has been reported that Interferon regulatory factor 1 (IRF1) inhibits Mycobacterium tuberculosis (Mtb) infection via inducible nitric oxide synthase (iNOS) in mice, how it counteracts with mycobacterial infection in human remains largely obscure. bis service manualWebSep 29, 2024 · Given that IRF-1 is well known to molecularly act downstream of IFN-γ signaling, we also subjected mice lacking IFN-γ to C. rodentium infection. However, compared to control mice, we observed no... darth maul shadow hunter pdfWebReference #: P10914 (UniProtKB) Alt. Names/Synonyms: Interferon regulatory factor 1; IRF-1; IRF1; MAR Gene Symbols: IRF1 Molecular weight: 36,502 Da Basal Isoelectric point: 5.22 Predict pI for various phosphorylation states Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® darth maul ruler of mandaloreWebDec 1, 2024 · LcIRF2, LcIRF5, LcIRF6, LcIRF10, and LcIRF11 have ORF of 954, 1476, 1473, 1206, and 792 bp, encoding 318, 492, 491, 402, and 264 aa, with a predicted molecular … bisset coupon carpet cleaningWebJul 8, 2024 · IRF1 expression is associated with the expression of IFNβ, which leads to the activation of the JAK-STAT pathway. Blocking the JAK-STAT pathway with the Janus kinase inhibitor (JAKinib)... darth maul screen used lightsaberWebIRF1 Protein Molecular Weight & PI . The parameters have been computed for the following feature . FT CHAIN 1-325 Interferon regulatory factor 1. Molecular weight (Da) 36502.21 … darth maul screams kenobi